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Tag: AstraZeneca


News

AstraZeneca, seeking new drug targets, taps a genomics biotech and its AI technology

September 8, 2023

Via: Biopharma Dive

Artificial intelligence tools have drawn the interest of many drugmakers hoping to use it to unearth new therapeutic targets. Launched in 2015, Verge has raised over $100 million from a variety of investors, including the asset management firm Blackrock and […]


Cell and Gene Therapy, Industry

AstraZeneca buys Pfizer’s early gene therapy work for up to $1B

July 28, 2023

Via: Biopharma Dive

Once a bystander in the field of genetic medicine, AstraZeneca has started to make its ambitions clear over the last couple years. The company stuck to the sidelines, while drugmakers such as Novartis, Bristol Myers Squibb and Gilead made significant […]


Mergers and Acquisitions

Revvity, AstraZeneca Enter Next-Gen Gene Editing Platform Pact

May 18, 2023

Via: Contract Pharma

Revvity, a provider of health sciences services, entered a new license agreement with AstraZeneca for the technology underlying its Pin-point base editing system, a next-generation modular gene editing platform with a strong safety profile. The Pin-point system and the underlying […]


News

EU clears AstraZeneca’s new-form severe asthma drug Tezspire

January 13, 2023

Via: Pharmaphorum

The green light for the pre-filled, single-use pen version of Tezspire (tezepelumab) comes just four months after the TSLP inhibitor became the first biologic therapy for severe asthma to be cleared in the EU for use in all patients, and […]


FDA, Regulations

AstraZeneca, Avillion get FDA approval for new ‘rescue’ drug for asthma

January 11, 2023

Via: Biopharma Dive

Airsupra is part of a growing portfolio of new drugs that are helping offset wilting sales of older AstraZeneca respiratory medicines such as Pulmicort. It’s an essential therapeutic area for the British drugmaker; in the third quarter, respiratory and immunology […]


Clinical Trials, Research and Development

RQ Bio-discovered antibody enters clinic as part of AstraZeneca COVID-19 study

January 4, 2023

Via: PMLiVE

The start of the trial triggers a $5m milestone payment from AZ, which licensed AZD3152 from RQ Bio in May last year, and reinforces the financial position of the UK-based biotech to execute its four scientific programmes focused on viral […]


Cell and Gene Therapy, Industry, Mergers and Acquisitions

AstraZeneca Acquires Neogene, Expanding in Cancer Cell Therapy

November 30, 2022

Via: GEN

AstraZeneca has agreed to acquire Neogene Therapeutics for up to $320 million cash, the companies said Tuesday, in a deal intended to bolster the buyer’s portfolio of cancer-fighting cell therapies. Neogene specializes in discovering, developing, and manufacturing next-generation T-cell receptor […]


Cell and Gene Therapy, Industry

AstraZeneca reveals its cell therapy ambitions with deal for startup

November 29, 2022

Via: Biopharma Dive

Once a fringe area of cancer research, cell therapy has exploded over the last decade. Since 2017, several treatments have come to market for blood cancers like leukemia and multiple myeloma, establishing cell therapy as a new class of medicines. […]


FDA, Regulations

AstraZeneca’s Imjudo/Imfinzi combination approved by FDA for unresectable liver cancer

October 24, 2022

Via: PMLiVE

The dosing schedule of the combination has been referred to as the STRIDE (Single Tremelimumab Regular Interval Durvalumab) regimen, which includes a single dose of Imjudo 300mg added to Imfinzi 1500mg followed by Imfinzi every four weeks. The approval is […]


FDA, Regulations

AstraZeneca gets first FDA okay for CTLA4 drug tremelimumab

October 24, 2022

Via: Pharmaphorum

Tremelimumab has been approved by the FDA in the US for use in tandem with AZ’s PD-L1 inhibitor Imfinzi (durvalumab) to treat adults with unresectable hepatocellular carcinoma (HCC), the most common tumour type affecting the liver. The CTLA4 inhibitor – […]


Mergers and Acquisitions

AstraZeneca to acquire gene editing biotech LogicBio

October 3, 2022

Via: Biopharma Dive

AstraZeneca’s rare disease unit Alexion will acquire gene editing specialist LogicBio Therapeutics in a small buyout deal, the companies announced Monday. Under the terms of the agreement, Alexion will acquire all of LogicBio’s outstanding shares for $2.07 each, representing a […]


FDA, Regulations

AstraZeneca, Daiichi breast cancer drug set for speedy FDA review

July 25, 2022

Via: Biopharma Dive

The Food and Drug Administration has agreed to quickly review AstraZeneca and Daiichi Sankyo’s drug Enhertu for treating metastatic breast cancer that expresses low levels of a protein known as HER2. If approved, the therapy would become the first targeted […]


Industry, Vaccines

Expert review shows AstraZeneca’s COVID-19 vaccine is ‘equally effective’ as mRNA vaccines

July 13, 2022

Via: PMLiVE

Infectious disease experts from Asia reviewed data from the VIEW-hub database on vaccine use and impact, developed by John Hopkins Bloomberg School of Public Health and the International Vaccine Access Center. The findings from the study were reported by Expert […]


News

Bristol Myers’ autoimmune drug shows potential in lupus

June 1, 2022

Via: Biopharma Dive

Until the launch of GSK’s Benlysta in 2011, people with lupus didn’t have a treatment option that targeted the disease’s underlying cause, relying instead on steroids and immunosuppressants to keep symptoms under control. AstraZeneca’s Saphnelo followed Benlysta to market in […]


Biotech, Industry

Innoviva buys struggling antibiotic biotech Entasis, as the AstraZeneca spin out preps FDA filing

May 23, 2022

Via: FierceBiotech

Holding company Innoviva is acquiring late-stage antibiotic biotech Entasis Therapeutics, a 2015 AstraZeneca spin-out that just posted phase 3 results worthy of an FDA filing last year. Innoviva already owns about 60% of Entasis’ outstanding shares. Under the new definitive […]


Biotech, Industry

AstraZeneca and Daiichi set to broaden use of breast cancer drug, challenging Roche

May 5, 2022

Via: Biopharma Dive

The approval of Enhertu as a second-line option further establishes the drug’s growing role in breast cancer, where it’s quickly becoming a go-to treatment for the roughly 15% of patients with HER2-positive disease. First conditionally approved for third-line use in […]


Industry, Vaccines

Poor countries reject COVID vaccines from AstraZeneca because of shorter shelf life: report

April 15, 2022

Via: FiercePharma

As supplies of COVID-19 vaccines have become more plentiful in poor nations, many are tuning down certain shipments. A document from the World Health Organization’s global vaccine supply effort COVAX shows that low-income countries have declined millions of doses of […]


FDA, Regulations

AstraZeneca and MSD’s breast cancer drug Lynparza receives FDA approval

March 15, 2022

Via: PMLiVE

The FDA approval is specifically for the treatment of patients with BRCA-mutated HER2-negative high-risk early breast cancer who have already received chemotherapy treatment either before or after surgery. As the most diagnosed cancer worldwide, an estimated 2.3 million patients were […]


Biotech, Industry

US vs EU: How can Europe translate home-grown innovation into biotech success?

January 26, 2022

Via: Pharmaphorum

From the Pfizer/BioNTech and Oxford/AstraZeneca vaccines to GSK’s lifesaving antibody treatments, European innovation has played a crucial role in the global response to COVID-19. But while the pandemic triggered a boom in biotech initial public offerings, according to Hannah Kuchler, […]


Industry, Vaccines

COVID vaccines help Pfizer, Moderna reign supreme reputation-wise, but they’re a double-edged sword for J&J and AZ

January 20, 2022

Via: FiercePharma

Pfizer and Moderna are now two of the leading pharma companies in the U.S. when it comes to public image, thanks to their COVID vaccines. On the flip side, vaccine rivals J&J and AstraZeneca have seen their reputations plummet. This […]