Tag: Antibody

Industry, Vaccines

Could Antibody Discovery Lead to Better Flu Vaccines?

December 29, 2023


Researchers appear to have discovered a new weapon in the war on a particularly difficult foe. They have identified a previously unrecognized class of antibodies that seem to be capable of neutralizing multiple strains of the flu virus. Their findings, […]

Clinical Trials, Research and Development

RQ Bio-discovered antibody enters clinic as part of AstraZeneca COVID-19 study

January 4, 2023


The start of the trial triggers a $5m milestone payment from AZ, which licensed AZD3152 from RQ Bio in May last year, and reinforces the financial position of the UK-based biotech to execute its four scientific programmes focused on viral […]

Clinical Trials, Research and Development

Uncommon Antibody Provides Ultrapotent Protection against Zika Virus

November 21, 2022

Via: GEN

In a study published in the journal Cell on November 18, a team led by scientists at Weill Cornell Medicine, and the National Institutes of Health (NIH) have isolated an uncommon and ultrapotent antibody that can neutralize the pathogenic zika […]


Engineered Antibody Shows Therapeutic Effects in Mouse Model of Alzheimer’s Disease

September 8, 2022

Via: GEN

A newly developed antibody that increases the activation of TREM2—a receptor on microglia—reduces amyloid burden and alleviates cognitive decline in mice exhibiting Alzheimer’s disease (AD) pathology. These findings indicate that the antibody, Ab18 TVD-Ig/aTfR, may have promise as a treatment […]

Industry, Vaccines

Powerful new antibody neutralizes all known SARS-CoV-2 variants

August 17, 2022

Via: World Pharma News

As SARS-CoV-2 has evolved and mutated, therapeutic antibodies that worked early in the pandemic have become less effective, and newer variants, especially Omicron, have developed ways to evade the antibodies we make in response to vaccines. A new, broadly neutralizing […]


New Drugs Provide Hope to Numerous Patients

February 22, 2022

Via: Natalie Dunn

As the Omicron variant of the virus that caused the current pandemic spreads and mutates, people are left hoping this will be the end of the healthcare crisis. Unlike previous variants, Omicron seems to be more infectious but less severe. […]

Industry, Vaccines

FDA Grants Emergency Use Authorization for New Antibody Drug Bebtelovimab to Fight Omicron Variant

February 11, 2022


The U.S. Food and Drug Administration on Friday gave the nod for a new monoclonal antibody treatment that works against the Omicron variant. The emergency use authorization for bebtelovimab is for the treatment of mild to moderate COVID-19 in adults […]

Industry, Vaccines

Nasal Vaccines May Offer Protection Against Different Viral Variants

December 13, 2021

Via: Genetic Engineering and Biotechnology News

The results of studies by researchers at Yale University have demonstrated how intranasal vaccination can provide broad-based protection against heterologous respiratory viruses in mice, while systemic immunization, which used an injection to elicit body-wide protection, does not. The studies, focused […]

Industry, Vaccines

Moderna, Regeneron warn about the effectiveness of COVID-19 drugs, vaccines against the omicron variant

November 30, 2021

Via: FiercePharma

As the world assesses the threat posed by the COVID-19 omicron variant, two top companies producing pandemic drugs and vaccines have warned that their current offerings may not be effective against the variant. On Tuesday, Regeneron sounded (PDF) a disquieting […]

Industry, Vaccines

AstraZeneca is nearly ready to seek approval for its COVID-19 antibody. Can it stick the landing?

September 30, 2021

Via: FierceBiotech

Across the first phase of the pandemic, AstraZeneca went from being a good example of how pharma can step up in times of need to a warning that no good deed goes unpunished. Now, AstraZeneca has a shot at putting […]

Industry, Vaccines

Study compares mRNA and adenovirus-based SARS-CoV-2 vaccines against variants of concern

July 26, 2021

Via: Medical News

The development and emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern that could potentially evade a vaccine-induced immune response is an ongoing concern, with the alpha (B.1.1.7), beta (B.1.351), gamma (B.1.248), and delta (B.1.614.2) lineages having […]

Industry, Vaccines

Durable antibody response at least 8 months following vaccination with J&J COVID vaccine

July 9, 2021

Via: Medical News

A recent study by a team of scientists at Beth Israel Deaconess Medical Center and Janssen Vaccines & Prevention has demonstrated that humoral and cellular immunity elicited by the coronavirus disease 2019 (COVID-19) vaccine Ad26.COV2.S remains active for at least […]

Industry, Vaccines

COVID-19 vaccines are effective in 94% of cancer patients, shows study

July 1, 2021

Via: Medical News

In a U.S. and Swiss study, nearly all patients with cancer developed good immune response to the COVID-19 mRNA vaccines three to four weeks after receiving their second dose, but the fact that a small group of the patients exhibited […]

Industry, Vaccines

New article explains the pros and cons of nasal vaccines

June 10, 2021

Via: Medical News

Vaccines are mostly synonymous with needles, an efficient and effective way to provide immunity to myriad infections. As COVID-19 vaccination efforts roll out across the U.S. and the world, some experts believe that a vaccine administered through the nose could […]

FDA, Regulations

FDA Approves Third COVID Antibody Treatment for Emergency Use

May 27, 2021


A third antibody treatment designed to keep high-risk COVID-19 patients from winding up in the hospital was approved for emergency use by the U.S. Food and Drug Administration on Wednesday. Importantly, in lab tests the newly authorized drug, dubbed sotrovimab, […]

FDA, News, Regulations

FDA fires broadside at CytoDyn over COVID-19 antibody data

May 19, 2021

Via: Pharmaphorum

It’s not uncommon for drug developers put a positive spin on lacklustre clinical data, but CytoDyn’s attempts seems to have irritated the US regulator, specifically relating to its use of subgroup analyses to try to indicate a benefit for leronlimab. […]


Eurofins Launches Quantitative Antibody Test to Measure Immune Response to COVID-19 and Vaccines

February 11, 2021

Via: BioSpace

Eurofins launches a new CE marked serological assay for the identification and quantification of antibodies to SARS-CoV-2. This ELISA kit can support vaccination campaigns by confirming the success of a vaccination and monitoring the antibody levels over time. Vaccination against […]

FDA, Regulations

FDA Authorizes Lilly COVID-19 Antibody Combination for Emergency Use

February 10, 2021

Via: Genetic Engineering and Biotechnology News

The FDA last night granted Emergency Use Authorization (EUA) for a 700 mg dose of bamlanivimab (LY-CoV555) in combination with a 1400 mg dose of a second Lilly antibody candidate, etesevimab (LY-CoV016), for the treatment of mild to moderate COVID-19 […]

Clinical Trials, Research and Development

Hemogenyx Pharmaceuticals PLC Announces Update on CDX Antibody Development

January 13, 2021

Via: BioSpace

Hemogenyx Pharmaceuticals plc (LSE:HEMO), the biopharmaceutical group developing new therapies and treatments for blood diseases, is pleased to announce that it has successfully completed the development of its CDX antibody with a leading global pharmaceutical company (“GlobalCo”). As a result […]

Cell and Gene Therapy, Industry

Antibody Response to Flu Shaped by Pre-Existing Immunity

December 14, 2020

Via: enetic Engineering and Biotechnology News

Receiving the seasonal flu vaccine each year, in addition to seasonal infections, exposes people to a lifetime of building up immune responses to influenza antigens. Yet, it remains unclear whether infection and vaccination induce distinct influenza-specific immunological memory. A team […]