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SARS-CoV-2 Infection Modeled in 3-D Stem Cell Culture Model

Understanding how SARS-CoV-2 infection damages the lungs is paramount to developing better treatments. Now, “mini-lungs” grown from tissue donated to Cambridge hospitals has provided a team of scientists with important insights into how COVID-19 damages the lungs. In new work, the researchers detail the mechanisms underlying SARS-CoV-2 infection and the early innate immune response in the lungs.

This work is published in Cell Stem Cell in a paper titled, “Three-dimensional human alveolar stem cell culture models reveal infection response to SARS-CoV-2.”

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