The first mouse model of pancreatic cancer that recreates two subtypes of the human disease, has been created by scientists at Cold Spring Harbor Laboratory (CSHL). Their model will help researchers investigate why some pancreatic cancers are more aggressive, and what causes them to progress. Their model may lead the way to targeted therapies.
Their study, “Intraductal transplantation models of human pancreatic ductal adenocarcinoma reveal progressive transition of molecular subtypes,” is published in Cancer Discovery.