Parkinson’s disease (PD) is a progressive disorder that affects nerve cells in the brain responsible for body movement. When dopamine-producing neurons die, symptoms such as tremor, slowness, stiffness, and balance problems occur.
Researchers at Carnegie Mellon University (CMU) have developed a new method for isolating a type of brain cell associated with Parkinson’s disease symptoms, enabling them to study that cell type in detail.
Their new method and findings are published in the journal JNeurosci in a paper titled, “Cell type-specific oxidative stress genomic signatures in the globus pallidus of dopamine depleted mice.”