An experimental drug appears to outperform the trendy medications Wegovy and Ozempic for both weight loss and diabetes control, a pair of early clinical trials shows.
Retatrutide helped people with obesity drop about one-quarter of their starting weight, on average, during 48 weeks taking the drug, according to phase 2 trial results published online June 26 in the New England Journal of Medicine.
“What is clear is that 24% weight loss from a single drug has not been seen before,” said co-researcher Dr. Lee Kaplan, an associate professor with Harvard Medical School. “And the subjects in the trial were still losing weight at the end.”
